Discovery Early Career Researcher Award - Grant ID: DE240100295

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE240100295

Funding Status
Active

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Funded Activity Summary

Unlocking the helminth ‘early infection gap’ using 3D cell culture models. This project aims to revolutionise the study of critical early host-parasite interactions using innovative 3D cell culture models, reducing our dependence on animal infections. Liver fluke is the most economically important zoonotic parasite of Australian livestock and is a significant contributor to global food insecurity. Due to the reliance of parasites on mammalian hosts to survive, very little is known about the early infection process. Expected outcomes include new knowledge on key migratory stimuli and liver fluke biology. Benefits include the identification of drug targets and vaccine candidates for use in livestock via the development of animal-free in vitro screening platforms that will serve as a prototype for other parasites.

Funded Activity Details

Start Date: 01-01-2024

End Date: 31-12-2026

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $455,563.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Host-parasite interactions | Invertebrate biology | Animal protection (incl. pests and pathogens) | Zoology

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Animal protection (incl. pests and pathogens) | Host-parasite interactions | Invertebrate biology | Veterinary Biological Preventatives | Veterinary Pharmaceutical Treatments | Zoology

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