Discovery Early Career Researcher Award - Grant ID: DE230101536

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE230101536

Funding Status
Active

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Funded Activity Summary

How does heme regulate blood vessel formation in the brain? There are more than 600 kilometres of blood vessels in the brain, all of which are lined by tightly packed cells that protect the brain from toxins. My research aims to investigate how these blood vessels are formed. This project expects to reveal the role that a critical signalling molecule called heme plays in this fundamental biological process. I will use cutting-edge structural biology and biophysical techniques to uncover the molecular mechanisms that allow heme to enter cells and regulate blood vessel growth in the brain. The outcomes of this research will enhance our understanding of the brain’s core infrastructure and will contribute to an understanding of how cerebral blood vessels grow and maintain integrity.

Funded Activity Details

Start Date: 31-12-2023

End Date: 30-12-2026

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $473,824.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Characterisation of biological macromolecules | Biochemistry and cell biology | Structural biology (incl. macromolecular modelling) | Receptors and membrane biology

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Biochemistry and cell biology | Characterisation of biological macromolecules | Expanding Knowledge In the Biological Sciences | Receptors and membrane biology | Structural biology (incl. macromolecular modelling)

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