Discovery Early Career Researcher Award - Grant ID: DE230100998

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE230100998

Funding Status
Declined

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Funded Activity Summary

Should I stay or should I go? How brain stem cells leave quiescence. Most adult stem cells in our brains are sleeping (quiescent). Quiescence helps ensure animals have a lifelong population of brain stem cells, which is crucial for the maintenance of brain circuitry. This project aims to investigate how this process is regulated at a molecular level. This project expects to define the molecular playbook controlling quiescence and explain why brain stem cells progress into deeper states of quiescence during aging by combining novel tissue culture and genetic models, where brain stem cells have disrupted quiescence, with innovative methods of reading gene expression. The benefits of these outcomes include the development of methods to control the quiescence of brain stem cells for bioengineering purposes.

Funded Activity Details

Start Date: Start date not available

End Date: End date not available

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $444,576.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular nervous system | Neurosciences

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Cellular nervous system | Expanding Knowledge In the Biological Sciences | Neurosciences

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