Discovery Early Career Researcher Award - Grant ID: DE230100634

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE230100634

Funding Status
Active

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Funded Activity Summary

Phos-Ligation: A powerful new tool for chemoselective protein modification. The project aims to develop a powerful new method for the generation of pure modified proteins. Tools for modification of proteins are integral to the study of protein structure and function as well as the commercial production of biopharmaceuticals. The extremely cost effective and operationally simple chemistry that will be developed in this project will overcome a number of pitfalls of currently available methods for protein modification, and will therefore deliver substantial technological innovation to both academia and industry. Through domestic and international collaboration, this new technology will be applied to study proteins involved in the defence of wheat against fungal rust disease and in inflammatory signalling in humans.

Funded Activity Details

Start Date: 16-01-2023

End Date: 15-01-2026

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $410,140.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Organic chemical synthesis | Proteins and peptides | Organic chemistry | Crop and pasture protection (incl. pests diseases and weeds)

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Crop and pasture protection (incl. pests diseases and weeds) | Expanding Knowledge In the Biological Sciences | Expanding Knowledge In the Chemical Sciences | Organic chemical synthesis | Organic chemistry | Proteins and peptides

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