Discovery Early Career Researcher Award - Grant ID: DE230100356

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE230100356

Funding Status
Active

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Bacterial membrane remodelling and the interaction with peptides. This project aims to elucidate the fundamental mechanism of lipid remodelling in Gram-negative outer membrane, which is critical both in preventing noxious compounds and evading host immune defence. For the first time, the complex interplays between bacterial cellular metabolism and membrane remodelling will be defined through systems pharmacology, and the precise membrane-peptide interaction will be examined by computational and biophysical approaches. Novel knowledge will be generated to improve our understanding on how bacteria remodel their outer membrane in response to environmental stress. This will benefit the future design of much-needed antimicrobial strategies including products and technologies to target bacterial membrane.

Funded Activity Details

Start Date: 01-01-2023

End Date: 31-12-2025

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $450,241.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Bacteriology | Proteomics and metabolomics | Pharmacology and pharmaceutical sciences | Basic pharmacology |

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Bacteriology | Basic pharmacology | Expanding Knowledge In the Biological Sciences | Expanding Knowledge In the Chemical Sciences | Pharmacology and pharmaceutical sciences | Proteomics and metabolomics

Related Links