Discovery Early Career Researcher Award - Grant ID: DE220101221

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE220101221

Funding Status
Active

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Revealing bat antibody recognition mechanism against bat-borne viruses. Bats act as asymptomic reservoir hosts for numerous zoonotic viruses that are lethal in humans, indicating that the bat immune system can control these viruses. However, little is known about bat immunity including how bat antibodies recognise bat-borne viruses. This project aims to study bat anti-viral antibodies by utilising innovative protein engineering, cutting-edge cryo-EM technology and single-cell isolation and sequencing. The project seeks to uncover bat-borne zoonotic virus glycoprotein architecture and reveal how bat antibodies function to inhibit viral infection. Expected outcomes will be new insight and tools to combat emerging and yet to emerge pathogens, enabling pandemic preparedness and increasing global biosecurity.

Funded Activity Details

Start Date: 31-12-2022

End Date: 30-12-2025

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $453,614.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Virology | Animal Immunology | Structural Biology (incl. Macromolecular Modelling) | Microbiology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Agricultural and Veterinary Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |

Other Keywords

Animal Immunology | Expanding Knowledge in the Agricultural and Veterinary Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences | Microbiology | Structural Biology (incl. Macromolecular Modelling) | Virology

Related Links