Discovery Early Career Researcher Award - Grant ID: DE220100823

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE220100823

Funding Status
Active

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Funded Activity Summary

Elucidating ATPase function during NLRP3 inflammasome assembly. Humans and animals are constantly exposed to microbes, which inhabit their external environment as well as body surfaces such as the skin and gut. We are, however, able to co-exist with these microbes, because our immune system protects us from these everyday encounters. This proposal will reveal how an important immune protein called NLRP3 senses microbes and other physiological processes. When NLRP3 senses such factors and is activated, it induces the release of messenger substances to alert other immune cells. This research will deliver fundamental knowledge of how animals normally co-exist with microbes.

Funded Activity Details

Start Date: 01-01-2022

End Date: 31-12-2024

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $442,482.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunology | Signal Transduction | Biochemistry and Cell Biology not elsewhere classified | Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology not elsewhere classified | Expanding Knowledge in the Biological Sciences | Immunology | Innate Immunity | Signal Transduction

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