Discovery Early Career Researcher Award - Grant ID: DE220100403

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE220100403

Funding Status
Active

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Funded Activity Summary

Defining how gut bacteria regulate metabolism: a role for gut serotonin. This project aims to understand how serotonin-producing cells in the gut interact with gut bacteria (the microbiome), using a combination of cells in culture and live germ-free and genetically modified mice. This project expects to generate new knowledge regarding cellular interactions that underlie important physiological pathways, such as the control of blood glucose and fat storage. The intended outcomes of this project are to identify how gut bacteria communicate with serotonin-producing cells to regulate metabolism, and whether diet acts via a gut microbiome-serotonin axis to impact physiology. The expected benefit of this project will be to provide a new understanding of highly complex physiological systems that regulate our health.

Funded Activity Details

Start Date: 01-01-2022

End Date: 05-02-2025

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $468,582.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Endocrinology | Metabolic Medicine | Cell Physiology | Medical Physiology |

ANZSRC Socio-Economic Objective (SEO)

Diabetes | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences

Other Keywords

Cell Physiology | Diabetes | Endocrinology | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences | Medical Physiology | Metabolic Medicine

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