Discovery Early Career Researcher Award - Grant ID: DE210101176

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE210101176

Funding Status
Active

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Funded Activity Summary

Fluorescent probes for super-resolution imaging of the amyloid architecture. The goal of this project is to develop chemical tools that enable molecular-level imaging of the amyloid structure. The Nobel Prize-winning super-resolution microscopy provides nanoscale imaging capabilities, but surprisingly there have been no substantive efforts to design fluorescent sensors that are compatible with this cutting-edge technology. In this project, new fluorescent super-resolution sensors will be developed that enable nanoscale visualisation of amyloid assemblies. These chemical and biochemical studies will establish rational design strategies to develop fluorescent sensors for super-resolution imaging applications and significantly advance our understanding of fundamental differences functional and toxic protein assemblies.

Funded Activity Details

Start Date: 30-06-2021

End Date: 29-06-2024

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $445,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Inorganic Chemistry | Bioinorganic Chemistry | Nanochemistry and Supramolecular Chemistry

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Bioinorganic Chemistry | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Inorganic Chemistry | Nanochemistry and Supramolecular Chemistry

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