Discovery Early Career Researcher Award - Grant ID: DE200101061

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE200101061

Funding Status
Active

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Funded Activity Summary

Single particle imaging: x-ray imaging of individual dynamic biomolecules. X-ray lasers produce powerful ultra-short pulses of light that can take temporal snap shots of small radiation-sensitive biological complexes. Thanks to superconducting technology, the next generation of x-ray lasers will be able to produce x-ray pulses at greater rates than ever before. But because of the sheer number of possible molecular configurations, these molecular movies will have only a small amount of data per frame, posing an enormous challenge for current imaging methods. I aim to meet this challenge by developing an innovative multi-conformational image reconstruction algorithm. This will provide a new window into the molecular dynamics of biological systems, the building blocks of life, and enable rational drug design.

Funded Activity Details

Start Date: 18-12-2020

End Date: 18-12-2023

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $424,848.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Optical Physics | Structural Biology (incl. Macromolecular Modelling) | Classical and Physical Optics | Atomic and Molecular Physics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Physical Sciences | Expanding Knowledge in the Biological Sciences | Application Software Packages (excl. Computer Games) |

Other Keywords

Application Software Packages (excl. Computer Games) | Atomic and Molecular Physics | Classical and Physical Optics | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Physical Sciences | Optical Physics | Structural Biology (incl. Macromolecular Modelling)

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