Discovery Early Career Researcher Award - Grant ID: DE200100074

Funding Activity

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Funded Activity Summary

Nanoscale laser cooling in physiological environment. By developing fluorescence pattern-based 3D motion-detection technology in optical tweezers, this project aims to reveal how to achieve nanoscale laser cooling in physiological media. It plans to discover new mechanisms of cooling associated with surface phonons and energy looping in optically trapped lanthanide-doped nanoparticles. Key expected outcomes are technology and a toolset to create interaction between cooled nanoscale objects and biological samples. These are expected to create a research area of biological laser refrigeration, enabling intracellular organelles cooling, nanoscale membrane disruption and high sensitivity force-sensing for integrin study for use in single-molecule biophysics and multimodality subcellular sensing.

Funded Activity Details

Start Date: 01-05-2020

End Date: 08-06-2022

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $418,210.00

Funder: Australian Research Council