Discovery Early Career Researcher Award - Grant ID: DE190100174

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE190100174

Funding Status
Closed

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Funded Activity Summary

Calcium-mediated regulation of stem cell development. This project aims to clarify the role of syndecan-mediated calcium in stem cell development using Caenorhabditis elegans. Stem cells have great potential for regenerative studies. While stem cells cultures are widely used, we do not fully understand how stem cells develop within an organism. This project expects to uncover the mechanisms underpinning calcium regulation by syndecan in stem cells. The expected outcomes include the optimisation of C. elegans stem cell methods to screen calcium regulating compounds and the creation of an in vivo calcium sensor. The project should advance knowledge of the role of syndecans in stem cells and provide the first analysis of in vivo calcium kinetics in stem cells.

Funded Activity Details

Start Date: 01-01-2019

End Date: 31-12-2021

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $400,747.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) | Medical Biotechnology | Regenerative Medicine (incl. Stem Cells and Tissue Engineering) | Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |

Other Keywords

Cell Development, Proliferation and Death | Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences | Medical Biotechnology | Regenerative Medicine (incl. Stem Cells and Tissue Engineering)

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