Discovery Early Career Researcher Award - Grant ID: DE190100116

Funding Activity

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Funded Activity Summary

Cell types and cell states revealed by single-cell regulatory networks. This project aims to use single-cell gene regulation networks to predict cell types. Computational approaches are needed to recapitulate how the over 37 trillion cells program the shared genome sequence in a human body to create astoundingly diverse forms and functions. This project integrates millions of high-resolution single-cell gene expression profiles with large-scale population regulatory data to systematically reconstruct gene regulatory networks. These networks are the molecular basis for understanding human cells. This projects outcomes intend to include the first reference single-cell regulatory database and novel methods and software to predict individual cells. This project will contribute to advancing Australia's capabilities in single-cell, precision medicine, and big biological data analysis leading to significant scientific, societal and commercial benefits.

Funded Activity Details

Start Date: 01-01-2019

End Date: 31-12-2021

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $415,737.00

Funder: Australian Research Council