Discovery Early Career Researcher Award - Grant ID: DE190100085

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE190100085

Funding Status
Closed

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Funded Activity Summary

Elucidating a novel mechanism for coping with harmful mutations. This project aims to improve our understanding of the complex regulatory mechanisms that increase genetic and phenotypic robustness. Survival of organisms depends on their ability to cope with genetic variation. A novel process of genetic compensation has recently been identified, producing a normal phenotype in a homozygous mutant, that would be expected to have deleterious effects. This project will reveal how compensation is achieved by examining the molecular pathways that are activated following genetic mutation. This project is expected to strengthen Australian reputation in evolutionary genetics, and in turn enhance our understanding of how organisms adapt to changing environments.

Funded Activity Details

Start Date: 01-02-2019

End Date: 30-09-2022

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $414,864.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene Expression (incl. Microarray and other genome-wide approaches) | Genome Structure and Regulation | Molecular Evolution | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Expanding Knowledge in the Biological Sciences | Gene Expression (incl. Microarray and other genome-wide approaches) | Genetics | Genome Structure and Regulation | Molecular Evolution

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