Discovery Early Career Researcher Award - Grant ID: DE170101438

Funded Activity Summary

Application of boronate ester-appended scaffolds in drug-discovery. This project aims to improve carbohydrate synthesis. Glycochemistry is an increasingly important chemical science that combines organic synthesis with biology. This project will develop methodologies that incorporate boronate ester residues onto selected carbons of monosaccharides and transform them to obtain hitherto inaccessible scaffolds for drug discovery. This strategy can be used in the controlled assembly of other biologically important compounds, including azacycles, oxacycles and inositols. The methods for the controlled diversification of carbohydrates are expected to be broadly applicable to scientific endeavours ranging from glycobiology to medicine. Successful execution will provide new drug-discovery tools and ensure Australia secures a competitive position in this rapidly expanding discipline.

Funded Activity Details

Start Date: 01-01-2017

End Date: 19-01-2017

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $360,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Organic Chemistry | Organic Chemical Synthesis | Biologically Active Molecules | Medicinal and Biomolecular Chemistry not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

Human Pharmaceutical Products not elsewhere classified | Crop Protection Chemicals | Human Pharmaceutical Treatments (e.g. Antibiotics) |

Other Keywords

Biologically Active Molecules | Crop Protection Chemicals | Human Pharmaceutical Products not elsewhere classified | Human Pharmaceutical Treatments (e.g. Antibiotics) | Medicinal and Biomolecular Chemistry not elsewhere classified | Organic Chemical Synthesis | Organic Chemistry

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