Discovery Early Career Researcher Award - Grant ID: DE170100112

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE170100112

Funding Status
Closed

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Funded Activity Summary

Epitranscriptomic regulation of learning and memory. This project aims to investigate m6A, the most prevalent internal modification in eukaryotic messenger RNA, in the mammalian brain. The adult brain contains a high level of reversible m6A, suggesting that m6A regulates the neuronal transcriptome during synaptic plasticity, the cellular basis of learning and memory. This project will use epitranscriptomics to investigate the more than 100 modifications on RNA, many of which are not yet characterised. Through molecular and mouse behavioural assays, the expected outcomes are insights into the post-transcriptional regulation underlying learning and memory, essential for survival in a constantly changing environment.

Funded Activity Details

Start Date: 01-01-2017

End Date: 30-06-2020

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $372,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System | Epigenetics (incl. Genome Methylation and Epigenomics) | Central Nervous System | Neurosciences

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Cellular Nervous System | Central Nervous System | Epigenetics (incl. Genome Methylation and Epigenomics) | Expanding Knowledge in the Biological Sciences | Neurosciences

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