Discovery Early Career Researcher Award - Grant ID: DE170100092

Funded Activity Summary

X-ray induced photoacoustic nanoprobe: Break depth dependency of bioimaging. This project aims to develop a nanoprobe using an X-ray excited luminescence “nanolaser” as the local light source to activate coupled responsive photoacoustic sensors. In-situ imaging of specific biomarkers at the molecular level is key to understanding their roles in physiological and pathological processes, but current imaging techniques using fluorescent probes cannot detect biomarkers in deep tissues due to shallow light penetration. By capitalising on the tissue penetrating property of X-rays and acoustic waves and collecting acoustic waves as the read-out signal, real-time monitoring of biomarkers in deep tissues could be achieved, advancing detection technology for deep-tissue biomarkers.

Funded Activity Details

Start Date: 09-01-2017

End Date: 31-12-2019

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $372,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Biotechnology Diagnostics (incl. Biosensors) | Biochemistry and Cell Biology | Analytical Biochemistry | Nanobiotechnology |

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in Technology

Other Keywords

Analytical Biochemistry | Biochemistry and Cell Biology | Expanding Knowledge in Technology | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Medical Biotechnology Diagnostics (incl. Biosensors) | Nanobiotechnology

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