Discovery Early Career Researcher Award - Grant ID: DE160100482

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE160100482

Funding Status
Closed

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Funded Activity Summary

Indoleamides as Molecular Interventions for Tuberculosis. This project aims to develop chemical probes capable of inhibiting the transport of essential mycolic acid across the cell wall of Mycobacterium tuberculosis. The emergence of resistant strains of Mycobacterium tuberculosis necessitates the identification of new, validated biological target(s) in the current control of tuberculosis. Preliminary data in this proposal demonstrate the discovery of indoleamides as a novel chemical entity. Development of these indoleamides may provide insights into a novel mechanism of action that could be targeted in combination with existing antitubercular agents.

Funded Activity Details

Start Date: 01-01-2016

End Date: 31-12-2018

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $364,536.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medicinal and Biomolecular Chemistry | Organic Chemical Synthesis | Biologically Active Molecules

ANZSRC Socio-Economic Objective (SEO)

Aboriginal and Torres Strait Islander Health - Health Status and Outcomes | Expanding Knowledge in the Chemical Sciences | Infectious Diseases |

Other Keywords

Aboriginal and Torres Strait Islander Health - Health Status and Outcomes | Biologically Active Molecules | Expanding Knowledge in the Chemical Sciences | Infectious Diseases | Medicinal and Biomolecular Chemistry | Organic Chemical Synthesis

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