Discovery Early Career Researcher Award - Grant ID: DE150101777

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE150101777

Funding Status
Closed

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Funded Activity Summary

Understanding the role of exosomes in intercellular communication. Exosomes, small packages released by cells, are powerful signalling organelles that can activate neighbouring cells by transferring proteins and RNA. Currently, it is unknown whether exosomes have similar membrane protein/lipid composition to that of the host cell. This project aims to explore the similarities and differences between the exosomal and host cell membranes in terms of the protein/lipid composition. In addition, the project aims to study how the proteins and RNA are packaged into exosomes. Membrane molecules that are detected only in the exosomes may have important signalling implications and may aid in the uptake/fusion of exosomes by/with target cells. The project aims to improve our understanding on signalling mediated by exosomes.

Funded Activity Details

Start Date: 01-01-2015

End Date: 31-12-2017

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $375,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Receptors and Membrane Biology | Bioinformatics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Bioinformatics | Expanding Knowledge in the Biological Sciences | Receptors and Membrane Biology

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