Discovery Early Career Researcher Award - Grant ID: DE150101755

Funding Activity

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Funded Activity Summary

Regulation of cell reprogramming to pluripotency by complex topographies. This project aims to use nanotopography approaches to improve the efficiency of generating induced Pluripotent Stem Cells (iPSCs) by changing cell behaviour at biomaterial surfaces. The significance is that iPSCs have enormous potential in stem cell therapy, regenerative medicine, and disease-specific treatment, with the potential to replace other stem cell types. The expected outcomes are that cellular reprogramming process for iPSCs generation will be improved and the canonical reprogramming factors might be reduced using surface nanotopographies of self-assembled colloidal crystals. The benefits are the promotion of productivity, the reduction of costs, and the application of iPSC derivatives, aimed at future clinical applications.

Funded Activity Details

Start Date: 27-06-2015

End Date: 26-06-2018

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $360,000.00

Funder: Australian Research Council