Discovery Early Career Researcher Award - Grant ID: DE150101481

Funded Activity Summary

Aquatic invasion of venomous snakes. Animal venoms target multiple physiological pathways to rapidly disrupt homeostasis and cause paralysis and death of prey animals. Physiological protein-encoding genes are recruited into the envenoming function, which then evolve to be highly effective on their molecular targets. The expansion of venom complexity due to the predator-prey chemical 'arms race' has given rise to a plethora of toxin types. While examples of venoms that have become subsequently streamlined and/or simplified in response to a change in environment and/or specialisation of diet are plenty, the underlying mechanisms remain elusive. This project aims to unravel how animal venoms become streamlined and uncover the underexplored vast pharmacopeia of aquatic venoms.

Funded Activity Details

Start Date: 01-01-2015

End Date: 31-12-2017

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $373,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Proteins and Peptides | Molecular Evolution | Medicinal and Biomolecular Chemistry | Biologically Active Molecules

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |

Other Keywords

Biologically Active Molecules | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Medical and Health Sciences | Medicinal and Biomolecular Chemistry | Molecular Evolution | Proteins and Peptides

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