Discovery Early Career Researcher Award - Grant ID: DE150100652

Funding Activity

Website
https://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE150100652

Funding Status
Closed

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Funded Activity Summary

Regulation of organ size and stem cell hierarchy in the developing kidney. Transient stem/progenitor cell populations play essential roles in establishing organ systems. The balance between self-renewal and differentiation in the nephron progenitor population plays a major, but poorly understood, role in regulating kidney development. Factors produced by undifferentiated progenitors promote organ expansion, whereas differentiation of these cells builds functional capacity. What is not clear is how the balance between self-renewal and differentiation is regulated in these cells, nor how the control of this fate decision impacts on optimal organ development. This project aims to dissect the molecular identity, regulation, and influence of this stem cell population on kidney development.

Funded Activity Details

Start Date: 09-02-2015

End Date: 31-07-2018

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $345,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Developmental Genetics (incl. Sex Determination) | Gene Expression (incl. Microarray and other genome-wide approaches) | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Developmental Genetics (incl. Sex Determination) | Expanding Knowledge in the Biological Sciences | Gene Expression (incl. Microarray and other genome-wide approaches) | Genetics

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