Discovery Early Career Researcher Award - Grant ID: DE150100019

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE150100019

Funding Status
Closed

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Funded Activity Summary

Protein network regulation: A systems-level analysis of methylation. The systems-level analysis of protein-protein interaction networks is a vital new framework for exploring protein complex formation. However key studies into the dynamics of these networks are being precluded by a lack of broad-scale data on interactions mediated by post-translational modifications, which are known regulators of protein-protein interactions. To solve this problem, this project aims to conduct an organism-wide survey of interactions mediated by an important class of post-translational modification, methylation, using an innovative mass spectrometry-based workflow. This project aims to produce fundamental new insights into the mechanisms underlying protein-protein interaction network dynamics, and into how protein complexes are formed.

Funded Activity Details

Start Date: 31-01-2015

End Date: 01-03-2019

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $352,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Proteomics and Intermolecular Interactions (excl. Medical Proteomics) | Biochemistry and Cell Biology | Systems Biology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Expanding Knowledge in the Biological Sciences | Proteomics and Intermolecular Interactions (excl. Medical Proteomics) | Systems Biology

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