Discovery Early Career Researcher Award - Grant ID: DE140101886

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE140101886

Funding Status
Closed

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Funded Activity Summary

Plant microRNA targeting: defining regulatory factors additional to complementarity. Central to our understanding of microRNA biology is the identification of which genes they target. In plants, high complementarity is regarded as the sole determinant, and drives bioinformatic predictions. However, functional evidence is inconsistent with this, arguing that complementarity alone is insufficient to accurately predict targets. This project uses novel applications of next generation sequencing to categorise bioinformatically predicted Arabidopsis targets as either strongly or poorly regulated. These categories will be analysed to determine what factors, in addition to complementarity, are required for strong targeting. The outcomes will impact artificial microRNA design and have important implications for biotechnology.

Funded Activity Details

Start Date: 30-09-2014

End Date: 30-09-2017

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $386,929.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene Expression (incl. Microarray and other genome-wide approaches) | Plant Cell and Molecular Biology | Plant Developmental and Reproductive Biology | Genetics

ANZSRC Socio-Economic Objective (SEO)

Industrial Crops not elsewhere classified | Plant Production and Plant Primary Products not elsewhere classified | Expanding Knowledge in the Biological Sciences |

Other Keywords

Expanding Knowledge in the Biological Sciences | Gene Expression (incl. Microarray and other genome-wide approaches) | Genetics | Industrial Crops not elsewhere classified | Plant Cell and Molecular Biology | Plant Developmental and Reproductive Biology | Plant Production and Plant Primary Products not elsewhere classified

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