Discovery Early Career Researcher Award - Grant ID: DE140101788

Funded Activity Summary

Structural Analysis of Biomolecular Complexes at Membrane Interfaces Important to Health and Disease. This project will study structural aspects of key biomolecular complexes at membrane interfaces that are involved with apoptosis (programmed cell death). Malfunctions in apoptosis have been implicated in many aliments including age-related diseases and cancers. Understanding of the molecular and structural aspects of key complexes can pave the way to novel therapies. The approach that will be used is to design new biomimetic outer mitochondrial membranes and use these to study the structure and binding of proteins involved with apoptosis. By studying simple models of complex systems, this project promises to yield detailed information on important biomolecular complexes where structural detail is currently lacking.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-03-2016

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $358,920.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Characterisation of Biological Macromolecules | Medicinal and Biomolecular Chemistry | Receptors and Membrane Biology | Colloid and Surface Chemistry

ANZSRC Socio-Economic Objective (SEO)

Human Diagnostics | Cancer and Related Disorders | Expanding Knowledge in the Biological Sciences |

Other Keywords

Cancer and Related Disorders | Characterisation of Biological Macromolecules | Colloid and Surface Chemistry | Expanding Knowledge in the Biological Sciences | Human Diagnostics | Medicinal and Biomolecular Chemistry | Receptors and Membrane Biology

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