Discovery Early Career Researcher Award - Grant ID: DE140100864

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE140100864

Funding Status
Closed

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Funded Activity Summary

Discovering The Effect of alpha-actinin-3 Deficiency on Muscle Adaptations to Exercise Training in Humans. The protein alpha-actinin-3 is expressed in fast muscle fibres. A common gene variant results in complete deficiency in alpha-actinin-3 that has been shown to influence athletic performance. A mouse model has been previously generated to demonstrate that alpha-actinin-3 deficiency results in a significant shift in fast muscle fibres, towards the slow, more efficient muscle fibres. This project will demonstrate the effects of alpha-actinin-3 deficiency on the characteristics of human muscle pre and post exercise training. Outcomes will include major applications for personalising health recommendations and in designing preventative programs for ageing.

Funded Activity Details

Start Date: 15-05-2014

End Date: 14-05-2017

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $394,334.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Exercise Physiology | Human Movement and Sports Science | Population, Ecological and Evolutionary Genetics | Cell Metabolism

ANZSRC Socio-Economic Objective (SEO)

Public Health (excl. Specific Population Health) not elsewhere classified | Expanding Knowledge in the Medical and Health Sciences |

Other Keywords

Cell Metabolism | Exercise Physiology | Expanding Knowledge in the Medical and Health Sciences | Human Movement and Sports Science | Population, Ecological and Evolutionary Genetics | Public Health (excl. Specific Population Health) not elsewhere classified

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