Discovery Early Career Researcher Award - Grant ID: DE140100624

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE140100624

Funding Status
Closed

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Funded Activity Summary

The impact of structural dynamics on three-dimensional bioimaging with X-ray free-electron lasers. X-ray lasers can potentially determine the structures of biological molecules that are inaccessible to existing techniques. Intense ultrafast pulses encode the structure via diffraction faster than damage processes rip the molecule apart. In fact, damage processes begin during diffraction and remain problematic. It is not known if damage will prevent the determination of molecular orientations, a critical step in the experimental design. This project will solve this problem with a statistical theory, probing the feasibility and accuracy of the technique. The newly developed theory will enable us to perform experiments capable of measuring the effects of damage in biological molecules, paving the way for new methods of structure determination.

Funded Activity Details

Start Date: 01-02-2014

End Date: 23-06-2017

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $372,529.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Optical Physics | Classical and Physical Optics | Atomic and Molecular Physics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Physical Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Atomic and Molecular Physics | Classical and Physical Optics | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Physical Sciences | Optical Physics

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