Discovery Early Career Researcher Award - Grant ID: DE140100500

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE140100500

Funding Status
Closed

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Funded Activity Summary

Unravelling the holistic genetic control of vertebrate development. Understanding the genetic regulation of embryo formation is the cornerstone of developmental biology. As four per cent of Australian children are born with some form of prenatal defect, understanding the basic biology of embryogenesis is paramount for long-range development of future therapies. We have identified a highly conserved transcription factor, Grhl3, which regulates multiple stages of embryonic formation. Using advanced genetic models, this project will characterise the role of Grhl3 in the regulation of cellular migration and craniofacial skeleton and brain development. The project will also identify the target genes which Grhl3 regulates. The identification of such transcriptional networks is imperative to understanding the holistic molecular control of embryogenesis.

Funded Activity Details

Start Date: 25-01-2014

End Date: 31-12-2018

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $383,066.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Cell Development, Proliferation and Death | Expanding Knowledge in the Biological Sciences

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