Discovery Early Career Researcher Award - Grant ID: DE140100320

Funded Activity Summary

Understanding cone photoreceptor migration and cell death mechanisms . Normal vision requires functional and correctly located cone photoreceptor cells. Many genetic mutations, however, impair the correct migration of these cells during development and ultimately cause cell death. This project will investigate, for the first time, the casual link between the migration of cone cells and activation of cell death mechanisms. A coordinated approach, using a range of molecular techniques, will be used to determine which factors are essential for normal development, correct spatial location and survival of cone photoreceptors within the mammalian retina. This will provide a major step forward in our knowledge of the processes involved in the spatial deployment of cones and the developmental organisation of the retina.

Funded Activity Details

Start Date: 30-09-2014

End Date: 31-12-2017

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $394,371.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene Expression (incl. Microarray and other genome-wide approaches) | Optometry and Ophthalmology | Vision Science | Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Hearing, Vision, Speech and Their Disorders |

Other Keywords

Cell Development, Proliferation and Death | Expanding Knowledge in the Biological Sciences | Gene Expression (incl. Microarray and other genome-wide approaches) | Hearing, Vision, Speech and Their Disorders | Optometry and Ophthalmology | Vision Science

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