Discovery Early Career Researcher Award - Grant ID: DE140100311

Funded Activity Summary

Mimicking nature: computational design of better antioxidants. The project will address a major challenge in biochemistry: how to design antioxidants that effectively scavenge harmful free radicals. This will involve the use of state-of-the-art quantum chemistry calculations to determine the molecular mechanisms of natural antioxidants and to design artificial antioxidants with higher efficacy. This project will introduce new concepts and methodologies that build on recent breakthrough research, revealing a novel mechanism of action of natural antioxidants. This will unravel the reaction mechanisms underlying defence against radical damage to key biomolecules, and will allow the design of bioinspired antioxidants for the treatment of oxidative-damage related diseases that affect millions of people.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-05-2017

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $395,220.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Theoretical and Computational Chemistry not elsewhere classified | Free Radical Chemistry | Theoretical and Computational Chemistry

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Free Radical Chemistry | Theoretical and Computational Chemistry | Theoretical and Computational Chemistry not elsewhere classified

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