Discovery Early Career Researcher Award - Grant ID: DE140100135

Funding Activity

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Funded Activity Summary

Understanding equine incretins: a novel approach to laminitis prevention. Laminitis is a crippling foot disease in horses which incurs significant economic and social costs. Recent studies have shown that persistently high insulin concentrations can trigger laminitis, and that high insulin levels are caused by the excessive release of hormones called incretins. This project aims to determine the role of incretins and their receptors in causing abnormal equine insulin secretion. The distribution of equine incretin receptors will be described for the first time, and the consequences of incretin receptor binding will be characterised. Understanding equine incretin biology may lead to novel therapies for laminitis.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-03-2017

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $395,199.00

Funder: Australian Research Council