Discovery Early Career Researcher Award - Grant ID: DE120101550

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE120101550

Funding Status
Closed

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Funded Activity Summary

Understanding multidrug resistance: identifying the molecular basis of substrate and inhibitor transport by P-glycoprotein. Chemotherapy resistance causes 90 per cent of cancer deaths and is commonly triggered by the increased activity of P-glycoprotein, which controls the cellular clearance of drugs. This project will determine how P-glycoprotein recognises and transports drugs, essential knowledge for the design of anticancer agents that can stop chemotherapy resistance.

Funded Activity Details

Start Date: 05-01-2012

End Date: 30-06-2016

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $375,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Proteins and Peptides | Characterisation of Biological Macromolecules | Biochemistry and Cell Biology | Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Cancer and Related Disorders | Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Cancer and Related Disorders | Characterisation of Biological Macromolecules | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Proteins and Peptides | Structural Biology (incl. Macromolecular Modelling)

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