Discovery Projects - Grant ID: DP1097033

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP1097033

Funding Status
Closed

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Funded Activity Summary

Single minded 1 in neuron development and satiety signalling. An understanding of how Single minded 1 (SIM1) regulates target genes may allow new pharmaceutical approaches to be designed to combat obesity. As Sim1 belongs to a family of closely related gene regulatory proteins which function in early development and homeostasis, deciphering the molecular control mechanisms of Sim1 may help understand how the related factors function in processes such as angiogenesis, response to low oxygen stress, invasion of environmental pollutants and autism spectrum diseases. The ability to manipulate these factors would be of great benefit in treating a range of disorders, but a thorough molecular understanding of these factors needs be obtained prior to attempting design of pharmaceuticals.

Funded Activity Details

Start Date: 2010

End Date: 12-2013

Funding Scheme: Discovery Projects

Funding Amount: $360,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurogenetics | Gene Expression | Genetics | Cell Neurochemistry

ANZSRC Socio-Economic Objective (SEO)

Endocrine organs and diseases (incl. diabetes) | Child health | Biological sciences |

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