Piezo2 and Pain - Is there a role for Piezo2 in mechanically induced bone pain?

Funding Activity

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Funded Activity Summary

Pain associated with bone marrow edema, osteoarthritis, bone cancer and fracture puts a significant burden on individuals, society, and the health care system in Australia. A dominant feature of these includes mechanical disturbances of the bone, and this is a trigger for the pain. In this study, we will determine if a newly discovered mechanically gated ion channel (Piezo2) is a key contributor to mechanically induced bone pain and could be a target for development of drugs to treat it.

Funded Activity Details

Start Date: 2018

End Date: 2020

Funding Scheme: Project Grants

Funding Amount: $543,848.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Sensory Systems

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity