Discovery Projects - Grant ID: DP0210076

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP0210076

Funding Status
Closed

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Funded Activity Summary

Genetic analysis of cohesin function and regulation in Drosophila. In yeast, a multiprotein complex, called cohesin, holds newly replicated chromatids together until the cell is ready to partition each chromatid into its daughter cells. We and others have shown that cohesins are regulated differently in animal cells. We propose to combine classical genetic analyses with two new and innovative techniques, time-lapse confocal microscopy of fluorescent proteins in living cells and gene-specific knockout techniques to study key cohesin regulators in Drosophila. These studies will provide us with novel insights into how multicellular organisms regulate the structure and stability of their chromosomes.

Funded Activity Details

Start Date: 2002

End Date: 12-2005

Funding Scheme: Discovery Projects

Funding Amount: $176,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Meiosis And Recombination | Biochemistry and Cell Biology | Gene Expression | Cell Development (Incl. Cell Division And Apoptosis)

ANZSRC Socio-Economic Objective (SEO)

Higher education | Biological sciences |

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