Website
http://dataportal.arc.gov.au/NCGP/API/grants/LP0211545
Funding Status
Closed
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Funded Activity Summary
Relaxin action in the heart, kidney, lung and uterus: understanding fibrosis. Relaxin is a peptide hormone associated with pregnancy. We have recently generated a relaxin gene knockout mouse and exciting preliminary data show that without relaxin, non-pregnant mice develop signs of fibrosis in the heart, lung and uterus. Combining our expertise in molecular biology, pharmacology and physiology, the overall objective of this project is to investigate the functions and mechanisms of relaxin action in these organs. Our findings will provide important basic information on relaxin physiology and enable us to implement a long-term partnership with Connetics to understand how relaxin regulates collagen production and/or the development of fibrosis.Funded Activity Details
Start Date: 2002
End Date: 12-2005
Funding Scheme: Linkage Projects
Funding Amount: $405,279.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Animal Physiology—Systems | Physiology
