Website
https://dataportal.arc.gov.au/NCGP/API/grants/DP150103990
Funding Status
Closed
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Funded Activity Summary
Nicotinic receptor structure and function probed with conotoxins. Nicotinic receptors are intrinsic membrane proteins that play a role in communication in excitable cells, particularly in the nervous system. The primary goals of this project are to define the structural and functional determinants of nicotinic-conotoxin interactions at a molecular level, and develop new selective probes that advance neurophysiological research. The diversity and distribution of nicotinic receptor subtypes being uncovered through molecular biology and selective conotoxin probes presents an exciting opportunity for the discovery of new therapeutic agents.Funded Activity Details
Start Date: 2015
End Date: 06-2021
Funding Scheme: Discovery Projects
Funding Amount: $634,100.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Medicinal and Biomolecular Chemistry | Biomolecular Modelling and Design | Receptors and Membrane Biology | Biologically Active Molecules
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |
