Discovery Projects - Grant ID: DP240102511

Funding Activity

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Funded Activity Summary

Touch and Tension: Molecular Determinants of Human Mechanosensation . Feelings of touch and muscle tension are initiated by mechanosensory neurons found within the peripheral nervous system. Knowledge of human mechanosensory neurons has predominantly relied on rodent studies because of the limited availability of human tissue, which is not ideal. Our team has developed novel technologies for generating human mechanosensory neurons ‘in the dish’. The major aim of this project is to use human stem cell-derived mechanosensory neurons as a platform to extensively study their molecular and functional properties. The significant benefits are the advancement of knowledge in the human mechanosensory system, which to date has been lacking, and in the long-term progress commercial development of novel drugs.

Funded Activity Details

Start Date: 2024

End Date: 12-2026

Funding Scheme: Discovery Projects

Funding Amount: $797,032.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular nervous system | Tissue engineering | Sensory systems | Neurosciences

ANZSRC Socio-Economic Objective (SEO)