Linkage Projects - Grant ID: LP0348921

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/LP0348921

Funding Status
Closed

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Funded Activity Summary

Development of Chemoenzymatic Methods for the Selective Elaboration of Polyfunctionalised Therapeutic Agents to Oligomers with Improved Efficacy. The aims of the project are to screen a novel collection of genetically engineered enzymes for their capacity to selectively manipulate proven therapeutic agents so that, ultimately, much more potent polymeric derivatives of the agent/drug can be obtained. The combined use of enzyme libraries and chemical manipulations to generate more powerful polymeric variants of already established drugs has never been undertaken previously in Australia. This approach has the capacity to generate hitherto inaccessible classes of therapeutic entities and to provide a new and unique technology platform for the country's biotechnology industry.

Funded Activity Details

Start Date: 11-2003

End Date: 12-2006

Funding Scheme: Linkage Projects

Funding Amount: $69,099.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Organic Chemistry | Biological And Medical Chemistry | Organic Chemical Synthesis |

ANZSRC Socio-Economic Objective (SEO)

Respiratory system and diseases (incl. asthma) | Prevention—biologicals (e.g. vaccines) | Treatments (e.g. chemicals, antibiotics)

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