Discovery Projects - Grant ID: DP160101623

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP160101623

Funding Status
Closed

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Funded Activity Summary

Single molecule intracellular intravital imaging of actin dynamics. The project intends to develop imaging technology to visualise fundamental processes in cells within a living animal. The focus will be on the actin cytoskeleton, a dynamic macromolecular machine involved in key cellular processes including cell structure, mobility and division. It is exquisitely sensitive to environmental perturbations, requiring it to be studied in cells in living tissue. The project aims to extend the resolution of live imaging to the single molecule to understand the dynamics of actin assembly with implications for cellular processes that are hijacked in diseases. It also aims to provide a novel assay that may enable testing of the impact of drugs on cellular processes in real time.

Funded Activity Details

Start Date: 2016

End Date: 12-2018

Funding Scheme: Discovery Projects

Funding Amount: $506,400.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Biochemistry and Cell Biology not elsewhere classified | Cancer Cell Biology |

ANZSRC Socio-Economic Objective (SEO)

Cancer and Related Disorders | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in Technology

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