Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP230101039
Funding Status
Active
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Funded Activity Summary
Uncovering an evolutionary advanced mechanism of gene expression control. This project aims to uncover a new mechanism that activates gene expression in mammals, which involves unexpected connections between the core components of chromosomes and essential enzymatic machines required for the expression of genes. This project will generate new knowledge on the poorly understood process of how the extensive genomic information of multicellular organisms is selectively chosen to enable the expression of only the required subset of genes. This will revolutionise our understanding of the mechanisms of gene control thereby shaping the field in the future. Significantly, this will allow new ways to manipulate gene expression that will impact biotechnology by providing new efficient ways to produce proteins or RNA.Funded Activity Details
Start Date: 2023
End Date: 12-2025
Funding Scheme: Discovery Projects
Funding Amount: $772,621.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Epigenetics (incl. genome methylation and epigenomics) | Structural biology (incl. macromolecular modelling) | Genetics | Genome structure and regulation
ANZSRC Socio-Economic Objective (SEO)
