Website
http://dataportal.arc.gov.au/NCGP/API/grants/FT190100559
Funding Status
Closed
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Funded Activity Summary
Metabolic control of organ growth and regeneration. One of the fundamental questions in biology is to understand how organ size is regulated at the cellular and organismal level. The Hippo/Yap pathway plays a central role in the regulation of organ size and it is impacted by environmental cues including nutrient status. This research proposal aims to use zebrafish to elucidate the role that the Hippo/Yap pathway plays in reprogramming lipid metabolism to fuel tissue growth in development and regeneration. Ultimately, this work aims to identify metabolic dependencies required for organ growth and regeneration. Expected outcomes include scholarly publications revealing fundamental principles underlying tissue growth, new resources for the research community and training for research students.Funded Activity Details
Start Date: 07-2019
End Date: 07-2019
Funding Scheme: ARC Future Fellowships
Funding Amount: $743,554.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Developmental Genetics (incl. Sex Determination) | Biochemistry and Cell Biology | Regenerative Medicine (incl. Stem Cells and Tissue Engineering) | Cell Metabolism
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |
