Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP200102693
Funding Status
Closed
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Funded Activity Summary
Adaptive reprogramming of metabolism in regeneration. . Biologists have long been intrigued at the phenomenon of organ regeneration. Unlike most human organs, the liver exhibits the remarkable capacity to regenerate. Despite decades of research, the molecular underpinnings of liver regeneration are poorly understood. This research proposal aims to use zebrafish to elucidate the pathways involved in sensing injury and activating an adaptive transcriptional and metabolic response to orchestrate regeneration. Ultimately, this works aims to understand the metabolic requirements for regeneration. Expected outcomes include scholarly publications revealing fundamental principles of regeneration, new resources and pipelines for the research community as well as training for research students.Funded Activity Details
Start Date: 2020
End Date: 12-2022
Funding Scheme: Discovery Projects
Funding Amount: $400,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Gene Expression (incl. Microarray and other genome-wide approaches) | Biochemistry and Cell Biology | Regenerative Medicine (incl. Stem Cells and Tissue Engineering) | Cell Metabolism
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |
