Discovery Early Career Researcher Award - Grant ID: DE140100963

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DE140100963

Funding Status
Closed

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Funded Activity Summary

Biofilms and quorum sensing in pneumococcal biology. Bacteria survive in their environmental niches by development of complex multicellular communities (biofilms), not by operating as individuals. Communication between bacteria is critical for biofilm formation, and is linked to their capacity to exchange DNA within and between species (competence). This is achieved by secretion and detection of small chemical signalling molecules (quorum sensing). Two such systems operate in the pneumococcus, a model Gram-positive organism. This project aims to elucidate the mechanism whereby these quorum sensing systems interact and collaborate to regulate biofilm formation and competence, phenotypes critical for bacterial survival. This knowledge will enable future development of novel antimicrobials.

Funded Activity Details

Start Date: 03-2014

End Date: 12-2017

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $395,220.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Microbiology | Bacteriology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |

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