Discovery Projects - Grant ID: DP0987763

Funding Activity

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Funded Activity Summary

Real-time imaging of the initiation of adaptive immunity in vivo. Understanding the first few hours of an immune response is fundamental to understanding how the human immune system functions. The immune system mounts our responses to infectious diseases, but can also cause autoimmune disease, allergy, and organ graft rejection. We will study how naive antigen-specific T cells first contact antigen in lymph nodes using 2-photon intravital microscopy. The research has the potential to change the way we think about the clonal selection of lymphocytes, the fundamental theory underlying our understanding of the immune system.

Funded Activity Details

Start Date: 03-2009

End Date: 03-2013

Funding Scheme: Discovery Projects

Funding Amount: $480,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autoimmunity | Immunology | Allergy | Cellular Immunology |

ANZSRC Socio-Economic Objective (SEO)

Immune system and allergy | Scientific instrumentation