Discovery Projects - Grant ID: DP180103974

Funding Activity

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Funded Activity Summary

Characterisation of vital carbohydrate synthases in pathogenic oomycetes. This project aims to understand the mechanisms that control cell wall stability in the fish pathogen, Saprolegnia parasitica. The biochemical properties and function of vital enzymes involved in cell wall biosynthesis will be determined using innovative approaches at the interface of biochemistry, microbiology, cell biology, and structural biology. Next generation ion mobility mass spectrometry will be used to solve challenging structural questions that cannot be tackled with conventional techniques. Expected outcomes include new knowledge on challenging membrane proteins that allows development of novel strategies for disease control in aquaculture. The data may also be applicable to crop protection from related plant pathogens.

Funded Activity Details

Start Date: 2018

End Date: 10-2021

Funding Scheme: Discovery Projects

Funding Amount: $546,441.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Mycology | Biochemistry and Cell Biology | Fish Pests and Diseases

ANZSRC Socio-Economic Objective (SEO)

Animal Welfare | Aquaculture Fin Fish (excl. Tuna) |