Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP0343130
Funding Status
Closed
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Funded Activity Summary
Monolayer crystallization of membrane proteins. Membrane proteins comprise 25-40% of all proteins and conduct a myriad of finely tuned reactions in every cell. Despite their importance and diversity only ~40 membrane protein structures have been solved, due to the difficulty of producing high quality 2D and 3D crystals. We propose to develop and use the new monolayer crystallization technique, which employs a lipid monolayer as a crystallization template for 2D crystal production. A number of important membrane proteins are available for these structural studies including ABC transporters, Caveolin-3 and the NS1 protein of Dengue virus, all of which are difficult to crystallize using conventional techniques.Funded Activity Details
Start Date: 2003
End Date: 06-2004
Funding Scheme: Discovery Projects
Funding Amount: $60,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Enzymes | Biochemistry and Cell Biology | Membrane Biology | Biophysics
