Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP220102030
Funding Status
Active
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Funded Activity Summary
Mechanisms maintaining mitochondrial copper homeostasis. This project aims to define the molecular mechanisms by which copper is trafficked and balanced within mitochondria. The project will employ an integrated biological, biochemical, biophysical and structural approach to examine the proteins which underpin the balance between the essentiality for copper and its toxicity, within this organelle. This project will deliver fundamental insights into how mitochondria contribute to and achieve cellular metal homeostasis, in addition to molecular explanations for how faults in this process result in mitochondrial defects. Major benefits include research training, strengthened international linkages and fundamental insights into mitochondrial biochemistry.Funded Activity Details
Start Date: 05-2022
End Date: 05-2025
Funding Scheme: Discovery Projects
Funding Amount: $550,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Biochemistry and Cell Biology | Structural Biology (incl. Macromolecular Modelling) | Bioinorganic Chemistry
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences |
