Website
http://dataportal.arc.gov.au/NCGP/API/grants/LX0452118
Funding Status
Closed
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Funded Activity Summary
Anti-ageing role for relaxin in blood vessels. Arteries stiffen with age. This is due to increased arterial smooth muscle tone and alterations in the extracellular matrix. In a sense, the artery undergoes ?fibrosis? with aging. In light of the anti-fibrotic attributes of the peptide hormone relaxin observed in other tissues, this collaborative project will investigate the potential role for relaxin in opposing arterial ?fibrosis? associated with aging. We will test the hypothesis that a reduction in arterial relaxin expression in older animals is a major cause of arterial stiffening. Further studies will investigate the mechanisms by which relaxin administration can alleviate this phenomenon.Funded Activity Details
Start Date: 01-2004
End Date: 12-2007
Funding Scheme: Linkage - International
Funding Amount: $39,356.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Animal Physiology—Systems | Physiology
