Discovery Projects - Grant ID: dp0344085

Funding Activity

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Funded Activity Summary

Development and Biological Chemistry of Novel Platinum Anti-Cancer Agents. "Rule-breakers", platinum anticancer complexes that do not follow the well established structure/activity relationships, have emerged as the way forward in the treatment of cancer resistant to the current generation of drugs and in reducing side effects. We have developed two new groups of "rule-breakers" and these have already demonstrated highly promising anticancer activity and novel biological behaviour. In this project we will (i) prepare new anticancer active platinum complexes based on these two highly promising groups of compounds and (ii) determine how these drugs work and what happens to them when in biological environments.

Funded Activity Details

Start Date: 03-2003

End Date: 02-2006

Funding Scheme: Funding Scheme not available

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Bioinorganic Chemistry | Inorganic Chemistry | Organometallic Chemistry

ANZSRC Socio-Economic Objective (SEO)

Treatments (e.g. chemicals, antibiotics) | Chemical sciences |